In patients with type 2 diabetes, beta-glucan reduces blood sugar through inhibition of SGLT-1 receptors in the intestinal mucosa. This is a receptor that helps absorb sugar in the intestine, thereby inhibiting the absorption of sugar in the intestine.

In a normal person, glucose from food is absorbed in the intestines into the bloodstream. Then, glucose from the blood is transported into cells for energy. Some glucose from the blood enters the liver to synthesize into glycogen stored in the liver. However, in diabetics this process is impaired. Studies have shown that beta-glucan promotes glycogen synthesis in the liver, inhibits the accumulation of fat in the liver, thereby reducing blood sugar.

In patients with type 1 diabetes, pancreatic islet cells are destroyed by the body’s own immune system, called an autoimmune mechanism. Pancreatic islet cells are responsible for producing insulin – the only hormone in the body that helps transport glucose from the blood into cells to lower blood glucose. When pancreatic islet cells are destroyed, the body completely lacks insulin, leading to hyperglycemia. Beta-glucan has an immunomodulatory effect, regulating the response of T lymphocytes to pancreatic islet 𝛽-cell antigens. Thus, reversing early-stage hyperglycemia in patients with type I diabetes.


More than 60% of diabetic patients have dyslipidemia. This is a factor that contributes to an increased risk of atherosclerosis and accelerates the progression of cardiovascular complications, the leading cause of death in diabetics.

Beta-glucan has been shown to lower LDL cholesterol and increase HDL-cholesterol in diabetics. Thus reducing the risk of atherosclerosis and cardiovascular complications. The mechanism of improving dyslipidemia of beta-glucan is as follows:

     – Beta-glucan can form a gel on the mucosal surface of the intestine. This inhibits intestinal reabsorption of bile salts. Meanwhile, the body needs bile salts to digest and absorb fats from food, so the liver must synthesize new bile salts. The process of synthesizing bile salts at the decanter requires the use of cholesterol in the blood. Thus lowering blood cholesterol levels…

    – Beta-glucan activates macrophages to help capture bad cholesterol circulating in the blood, phagocytize (eat) plaques that are considered foreign objects on the artery walls.

    – Beta-1,3/1,4-D glucan in barley forms a gel in the intestinal mucosa that reduces fat absorption in the intestine.


High blood sugar in diabetics increases the risk of infection. In addition, damage to blood vessels also reduces blood flow to the wound. Thereby reducing the healing factors that make the wound heal longer, especially the foot ulcer complication in diabetic patients. One of the effects of Beta-Glucan for diabetics is to promote wound healing by increasing the infiltration of macrophages to remove lesions at the wound, stimulating granulation tissue formation, collagen deposition and regeneration. create epithelium.


In diabetics, high blood sugar leads to an overproduction of free radicals. Excess free radicals are the agents that destroy the vessel walls and lead to a series of diabetic complications on nerves, eyes, heart, kidneys, etc.

Beta-glucan has the effect of scavenging ROS free radicals including OH-, H2O2, O2-… The high antioxidant mechanism of beta-glucan can be attributed to the presence of anomeric Hydrogen atoms in its molecule. and the macromolecular structure provides free radical scavenging. Therefore, beta-glucan has an inhibitory effect on oxidative stress in diabetics, helping to prevent and slow the progression of complications. Research has shown beta-glucan reduces oxidative stress in the brain and sciatic nerve of diabetics and can be used as a protector against brain damage and diabetic sciatica.


Different beta-glucan products have different qualities. In order to choose a product with high quality and effectiveness, diabetics should note the following criteria:

     – Choose products that contain beta-1,3/1.6-D-glucan instead of beta 1,3/1.4 D-glucan because studies have shown beta-1,3/1.6- D-glucan is more active.

    – Carefully check the content of beta-1,3/1.6-D-glucan because the product label may state the total beta-glucan content containing many different types of beta-glucan at the link. However, the content of beta-1,3/1.6-D-glucan in the total amount of beta-glucan is the value that determines the effectiveness of the product.

Beta-glucan can now be produced by chemical and biological methods. However, you should choose products that are produced by biological methods or enzyme technology because this method preserves the original structure of beta-1,3/1.6-D-glucan, obtain high purity beta-glucan and reduce environmental pollution.

One of the beta-glucan products that many experts and patients appreciate and trust today is BGPlus. Beta-Glucan in BGPlus is extracted by enzyme technology from the yeast cell wall Saccharomyces cerevisiae with high purity. This is a research achievement between the Center for Research and Application of Biotechnology and Environment under BCC Pharma Joint Stock Company and the Institute of Biotechnology – Vietnam Academy of Science and Technology. “ Promoting innovation through research, science and technology”  (FIRST Project) of the Ministry of Science and Technology.

In addition to 120mg of beta-1,3/1.6-D-glucan, BGPlus also adds cordyceps to help strengthen immunity, increase blood circulation, absorb nutrients, and maintain a healthy body. With Nano Curcumin, it helps to reduce blood sugar, promote wound healing, lower blood cholesterol and B vitamins to support digestion and nerves.